Histology and histopathology Vol. 6, nº 2 (1991)
Ir a Estadísticas
Permanent URI for this collection
Browse
Recent Submissions
- PublicationOpen AccessUltrastructural study of bronchial epithelium in chronic respiratory diseases(Murcia : F. Hernández, 1991) Kaidoglou, K.; Aivazis, V.; Alvanou, A.; Saricos, G.; Tzimakas, Chr.; Foroglou, Ch.The fine structure of bronchial epithelium in thirt!,-six patients. thirty-one men and five women. suffering from chronic obstructive pneumonopathy or bronchial carcinoma was studied. No remarkable alterations were found with electron microscopy. in most non-smokers in contrast to the smokers who presented destruction of tlie epithelial cells and loss of thc cilia or many pathological cilia with an abnormal microt~~bular configuration and irregular orientation. The severity. however. of the alterations was not related to the severity of smoking and to the presence of bronchial cancer.
- PublicationOpen AccessAmitosis in human adrenal cells(Murcia : F. Hernández, 1991) Magalhães, M. C.; Pignatelli, D.; Magalhães, M. M.Adrenal pieces obtained from 3 fcmalc ancl 2 ~nirle patients sho\\'cd morpl~ologicirl figures of umito4is in aclrcnirl zona ret ic~~l :~rcicsl ls. Such aspects were ohs c r \~~i~n cblo th normal and hyperactive aclrcnuls. Nuc,lci appeal-cd constricted. hea\ ill stained. \\.it11 coarse chromatin. sometimes scattered among c!toplasmic organcllcs. hut never niarginating in cre4ccntic cirps. C'lea\:~gc 01' the cells originated t\\lo hnl\,cs \\it11 a nucleolus in each pole. Rin~lcleateclc clls \vcl-c also seen in zona rcticularis. -1~Iie meaning ot' nmitosis in human aclren:rl i4 cIisc11~4ccI.
- PublicationOpen AccessDevelopment of the small intestine of piglets in response to prenatal elevation of glucocorticoids(Murcia : F. Hernández, 1991) Bate, L.A.; Ireland, William P.; Connell, B.J.; Grimmelt, B.The effects of prenatal adrenal stimulation and synthetic glucocorticoicl supplementation on developrncnt of the gastro-intestinal tract of the piglet were investigated. Twelve pregnant sows were treated with either ACTH infusion. Isoflupredone injection or Saline between days I05 and 112 of gestation. Neonatal pigs were weighed. bled and sacrificed at 0 or at 6 h. Piglets sacrificed at 6 h were fed bovine colostrum. Trailsvcrse sections were prcpared from the duucienuin. i e j ~ ~ n uman cl ileum for measurcment of thc villus amplification factor (VAF) and basal membrane circunifercnce. Sows in the ACTH group showed an cle\,ation in cortisol in response to infusion: this decreased aftcr infusion and then rose again at parturition. Piglcts from both the ACTH and Saline groups had more villus surface area per unit of body weight (BW) than those born to Isotluprcdone-treated animals. The BW of the ACTH piglets was lowcr (P < 0.05) than those of piglets in the other groups. Whcn the weight of thc stomach and the Small Intestine (SI) was cxpressetl as a function of thc body weight, tlic stomach and S1:BW ratio was larger (p < 0.05) in pigs born to ACTH-treated sows. The circumfcrence of the ilcurn was larger at 6 h than at 0 h. Control pigs had a higher concentration of bovine IgG at 4 and 6 h (P < 0.05). Observations of thc light microscvpic preparations indicated a less organized epithelium in both ACTH and isotluprcdone pigs sacrificed at O Ii. Light and EM preparations of ileum from ACTH pigs sacrificed at 6 h. showcd an abundance of dark-stained vacuoles. characteristic of IgG-containing structures. These became lcss evident in piglets from the Isotlupredone group and even less so in thc control groups. The consequences of these phenomena in terms of absorptive capacity are discusscd.
- PublicationOpen AccessResponses of the astroglia in sensory deprived olfactory bulb of developing rats(Murcia : F. Hernández, 1991) Martinez Garcia, Ma del Carmen; Cuervas-Mons, M.; Latorre Macarron, Emilia; Bullon Sopelana, Ma Manuela; Gayoso Rodriguez, Manuel J.The effects of ~rnilateral olfactor!, depri\,ation on tlie glial population during the olf~lctory h~llh tle\,clopmcnt lin\je hecn sturliecl. The lack of sensor! stimulation has hcen founcl to he related to an increase in gliofihril1;rry acirl protein (GFAP) in the tliree la!ers of tlic rlzprivcd bulbs. This increase is due to the lli~liern umber of aitrocytes in tlie depri\-ecl hulh. \vliicli is m~ ~ cml io re noticeable in the plcxifo~ml ayer than in tlic other t\jlo. together with :I Ii!.pertrol7li! of the rcacti\e irstrocytes resulting in an increase in tlie n~lmher ancl thickness of their prolongation\. Our results clcmonst~.ate that scnsory olfactor! depri\,ntion acts as other noxius agents on the CNS. causing gliosis in the olfactory hulb. This gliwis is revcalerl h!' astrr)c!,tic liyperplasia allcl Iiyp~rtropli!~.
- PublicationOpen AccessComparative morphological studies of lamb and calf Sertoli cells treated with anabolic agents(Murcia : F. Hernández, 1991) Rodríguez Barbudo, M. V.; Mendez Sanchez, A.; Blanco Rodriguez, A.The morphological alterations caused by anabolic steroicls (oestradiol and trenbolone acetate) 011 the Sertoli cells of testicles in animals for human consumption (lambs and calves) were studied. The morphopathological study of the treated lambs revealcd delayed devcloptnent of thc scminiferous tubules, which was marked by signs of immaturity and even degeneration of Sertoli cells. The tnain n~orphopathological alterations affecting the Sertoli cells in calves occurred as hyperfunction symptoms marked by increascd nuclei and smooth endoplasmic reticulum.