Publication:
The thyroid gland of Callithrix jacchus in organ culture

Simple item page
dc.contributor.authorMaile, S.es
dc.contributor.authorMerker, H. J.es
dc.date.accessioned2011-02-22T10:31:09Z
dc.date.available2011-02-22T10:31:09Z
dc.date.issued1995
dc.description.abstractThyroid glands from 7 marmosets (Callithrix jacchus) of different age groups (newbom, 2 weeks, 2,7, 8 and 11 months, and 8 years) were grown as organ culture according to Trowell at the mediumlair interphase for 3 to 30 days. The morphology of thyroid tissue was well preserved until the end of the culture period. Necroses were only occasionally seen in connective tissue. In contrast to the in vivo situation, the number of lysosome-like inclusions changed considerably and cell-cell contacts became loose. After the addition of TSH the number of apical microvilli, apical granules and coated vesicles rose. The basa1 surface of follicle cells enlarged due to the formation of processes or ridges and invaginations. Mitosis could be observed. These findings show that, using the Trowell culture technique, thyroid tissue can be grown for up to 4 weeks without showing distinct changes in its morphology. Its responsiveness to the application of TSH is maintained in vitro. Hence, this technique is suitable also for long-term endocrinological, pharmacological and toxicological investigations.es
dc.formatapplication/pdfes
dc.format.extent17es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18773
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectThyroid glandes
dc.subjectLong-term organ culturees
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleThe thyroid gland of Callithrix jacchus in organ culturees
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
The thyroid gland of Callithrix jacchus in organ culture.pdf
Size:
2.28 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Histology and histopathology Vol.10, nº 4 (1995)