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Reorganization of the subplasmalemmal cytoskeleton in association with exocytosis in rat mast cells

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dc.contributor.authorHolm Nielsen, E.es
dc.contributor.authorBraun, K.es
dc.contributor.authorJohansen, T.
dc.date.accessioned2011-02-22T10:29:20Z
dc.date.available2011-02-22T10:29:20Z
dc.date.issued1989
dc.description.abstractThe subplasmalernmal cytoskeleton in mast cells has been studied by scanning electron microscopy of the internal side of the plasma membrane. Rearrangement of the dense subplasmalemmal network of actin filaments took place following cell activation by compound 48/80 and secretion of histamine. The rearrangement was a withdrawal of the subplasmalemmal cytoskeleton from the exocytotic sites and the development of bare, filament-free areas around the sites. In calciumdepleted mast cells we demonstrated a dense network that was difficult to break. Activation of the calciumdepleted cells by compound 48/80 did not induce rearrangement of the network, and in parallel there was no secretion of histamine.es
dc.formatapplication/pdfes
dc.format.extent5es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18691
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectMast cellses
dc.subjectCytoskeletones
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::615 - Farmacología. Terapéutica. Toxicología. Radiologíaes
dc.titleReorganization of the subplasmalemmal cytoskeleton in association with exocytosis in rat mast cellses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 4, nº 4 (1989)