Histology and histopathology Vol. 4, nº 4 (1989)
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- PublicationOpen AccessCompensatory adrenal growth in aldosterone-treated male and female hamsters(Murcia : F. Hernández, 1989) Kasprzak, A.; Malendowicz, L.K.The aim of the study was to investigate the compensatory adrenal growth in aldosterone-treated male and female hamsters. Hemiadrenalectomised and sham-operated animals were treated for 5 days with a daily d-aldosterone dose of 25 pglanimal. In both male and female aldosterone-treated hamsters monoadrenalectomy did not change the relative adrenal weight if compared with sham-operated groups. The fasciculata zonae of monoadrenalectomised aldosterone- treated males was larger and contained more parenchyma1 cells than in appropriate control group. There was no difference in the volume of adrenocortical zones, average cell volume and in cell number between sham-operated and unilaterally adrenalectomised females. In vitro 3H-thymidine incorporation per adrenal was markedly higher in monoadrenalectomised than in sham-operated aldosterone-treated males while the opposite was true for female hamsters. Thus, the action of aldosterone on CAG in the hamster seems to depend on sex, with no effect in males and inhibitory action in females.
- PublicationOpen AccessThe effects of CDP-choline on newborn rat pups with experimental alcohol fetopathy. A Golgi study(Murcia : F. Hernández, 1989) Patt, Stephan; Cervós-Navarro, J.; Stoltenburg-Didinger, G.; Schreiner, C.Generally accepted features of alcoholic fetopathy are delayed maturation and retarded dendritic development of neocortex, hippocampus and cerebellum. The present study investigates the effects of a membrane stabilizing agent (CDP-choline) on Purkinje cells of chronically alcohol intoxicated newborn rat pups, employing a Golgi impregnation technique. Both quantitative and qualitative data indicate that CDP-choline modifies the alcohol induced lesion.
- PublicationOpen AccessMuscle regeneration induced by snake venom. A histological and histochemical study(Murcia : F. Hernández, 1989) Peña, J.; Jimena, I.; Luque, E.; Martín, J.D.; Vaamonde, R.This report describes the regeneration pattern of anterior tibial muscle of the rat after the inoculation of the snake venom of Bothrops jararacussu . The results show that this regeneration pattern is rather similar to the pattern described in other experimental models. Three days after the injection, three differentiated areas are established: a periferic one of surviving fibres, a second one called myogenic area, and the last one, more internal, made of necrotic fibres that are phagocited by macrophages. The surface of the surviving muscle fibres has myoblasts sticking to it and five days after, the myogenic area is occupied by many of them. Both the previous phagocytosis and the myoblasts came from the area of current uninjured fibres. After 30 and 60 days the regeneration is completed and there are only a few marks that show that the regeneration has taken place.
- PublicationOpen AccessEpidermal Langerhans cells in infectious diseases(Murcia : F. Hernández, 1989) Tapia, F.J.; Cáceres-Dittmar, G.; Acuña, Lourdes; Mosca, Walter
- PublicationOpen AccessThe phylogenetic odyssey of the erythrocyte. I Hemoglobin: the universal respiratory pigment(Murcia : F. Hernández, 1989) Glomski, Chester A.; Tamburlin, JudithHemoglobin is a molecular entity that is capable of reversibly binding and releasing oxygen in either extra- or intracellular milieus. It is present in scattered invertebrates in physical solution or in cellular sites while in vertebrates it is universally located in circulating erythrocytes. These cells serve as the vehicle for and otherwise foster the optimum utilization hemoglobin. Hernoglobin's variable sphere of respiratory activities can be viewed as reflecting the specific requirements for each organism in which it is observed. Once these concepts have been established and the advantages and limitations of its cytologic packaging recognized, the study of the erythrocyte as expressed in its dimensions, colligative aspects, geometry, internal morphology and pathologic variations can be approached in a purposeful manner.