Publication: Phagocytosis in teleosts. Implications of the new cells involved
Authors
Chaves-Pozo, Elena ; Meseguer, José ; Cuesta Peñafiel, Alberto ; Esteban Abad, María de los Ángeles
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Publisher
MDPI
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DOI
doi:10.3390/biology4040907
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info:eu-repo/semantics/article
Description
Abstract
Phagocytosis is the process by which cells engulf some solid particles to form
internal vesicles known as phagosomes. Phagocytosis is in fact a specific form of endocytosis
involving the vesicular interiorization of particles. Phagocytosis is essentially a defensive
reaction against infection and invasion of the body by foreign substances and, in the
immune system, phagocytosis is a major mechanism used to remove pathogens and/or cell
debris. For these reasons, phagocytosis in vertebrates has been recognized as a critical
component of the innate and adaptive immune responses to pathogens. Furthermore, more
recent studies have revealed that phagocytosis is also crucial for tissue homeostasis and
remodeling. Professional phagocytes in teleosts are monocyte/macrophages, granulocytes
and dendritic cells. Nevertheless, in recent years phagocytic properties have also been
attributed to teleost lymphocytes and thrombocytes. The possible implications of such cells
on this important biological process, new factors affecting phagocytosis, evasion of
phagocytosis or new forms of phagocytosis will be considered and discussed.
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Citation
Biology 4:907-922
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