Publication: Mobility limitations related to reduced pulmonary function amongaging people with chronic obstructive pulmonary disease
Authors
Medina i Mirapeix, Francesc ; Bernabeu Mora, Roberto ; Sánchez Martínez, Mª Piedad ; Montilla Herrador, Joaquina ; Myriam Bernabeu Mora ; Escolar Reina, Pilar
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Facultades de la UMU::Facultad de Medicina
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Publisher
Plos One
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DOI
https://doi.org/10.1371/journal.pone.0196152
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info:eu-repo/semantics/article
Description
Abstract
Background
Chronic obstructive pulmonary disease (COPD) is a major cause of disability. We aimed to
analyse the impact of reduced pulmonary function on non-respiratory impairments and
mobility activity limitations in an elderly population with COPD and to elucidate which spe
cific limitations on mobility are related to reduced pulmonary function
Methods
Cross-sectional study of 110 patients with COPD, recruited from public and university hospi
tal. The effect of impaired pulmonary function on the risk of non-respiratory impairments and
mobility limitations was analysed using validated measures, including: the 6-Minute Walk
Test (6MWT), skeletal muscle strength, the Short Physical Performance Battery (SPPB),
andself-reported mobility questionnaire. Multivariate analysis was used to control for con
founders such as age, sex, height, education, and cigarette smoking.
Results
Greater impairment of pulmonary function was associated with less distance walked during
the 6MWT,poorerSPPBscores,andgreater risk of self-reported mobility limitations
(p<0.05). Lower forced expiratory volume in 1 s was also associated with a greater risk of
limitations in carrying items under 10 pounds (4.54 kg), walking alone up and down a flight
of stairs, and walking two or three neighbourhood blocks. There was no clear statistical rela
tionship between pulmonary function impairment and skeletal muscle strength.
Conclusions
Impaired pulmonary function was associated with the 6MWT score and limitations on perfor
mance-based and self-reported mobility activities, but not with skeletal muscle strength
amongelderly COPDpatients
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Citation
Medina-Mirapeix F, Bernabeu-Mora R, Sánchez-Martínez MP, Montilla-Herrador J, Bernabeu-Mora M, Escolar-Reina P (2018) Mobility limitations related to reduced pulmonary function among aging people with chronic obstructive pulmonary disease. PLoS ONE 13(5): e0196152
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