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Mobility limitations related to reduced pulmonary function amongaging people with chronic obstructive pulmonary disease

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dc.contributor.authorMedina i Mirapeix, Francesc
dc.contributor.authorBernabeu Mora, Roberto
dc.contributor.authorSánchez Martínez, Mª Piedad
dc.contributor.authorMontilla Herrador, Joaquina
dc.contributor.authorMyriam Bernabeu Mora
dc.contributor.authorEscolar Reina, Pilar
dc.contributor.departmentFisioterapia
dc.contributor.otherFacultades de la UMU::Facultad de Medicina
dc.date.accessioned2026-02-24T12:23:05Z
dc.date.available2026-02-24T12:23:05Z
dc.date.copyright© 2018 Medina-Mirapeix et al.
dc.date.issued2018-05-01
dc.description.abstractBackground Chronic obstructive pulmonary disease (COPD) is a major cause of disability. We aimed to analyse the impact of reduced pulmonary function on non-respiratory impairments and mobility activity limitations in an elderly population with COPD and to elucidate which spe cific limitations on mobility are related to reduced pulmonary function Methods Cross-sectional study of 110 patients with COPD, recruited from public and university hospi tal. The effect of impaired pulmonary function on the risk of non-respiratory impairments and mobility limitations was analysed using validated measures, including: the 6-Minute Walk Test (6MWT), skeletal muscle strength, the Short Physical Performance Battery (SPPB), andself-reported mobility questionnaire. Multivariate analysis was used to control for con founders such as age, sex, height, education, and cigarette smoking. Results Greater impairment of pulmonary function was associated with less distance walked during the 6MWT,poorerSPPBscores,andgreater risk of self-reported mobility limitations (p<0.05). Lower forced expiratory volume in 1 s was also associated with a greater risk of limitations in carrying items under 10 pounds (4.54 kg), walking alone up and down a flight of stairs, and walking two or three neighbourhood blocks. There was no clear statistical rela tionship between pulmonary function impairment and skeletal muscle strength. Conclusions Impaired pulmonary function was associated with the 6MWT score and limitations on perfor mance-based and self-reported mobility activities, but not with skeletal muscle strength amongelderly COPDpatients
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dc.identifier.citation Medina-Mirapeix F, Bernabeu-Mora R, Sánchez-Martínez MP, Montilla-Herrador J, Bernabeu-Mora M, Escolar-Reina P (2018) Mobility limitations related to reduced pulmonary function among aging people with chronic obstructive pulmonary disease. PLoS ONE 13(5): e0196152
dc.identifier.doihttps://doi.org/10.1371/journal.pone.0196152
dc.identifier.eissn1932-6203
dc.identifier.urihttp://hdl.handle.net/10201/212141
dc.languageeng
dc.publisherPlos One
dc.relationAstraZeneca Pharmaceutical Spain, S.A. funded manuscript translation from a first version in spanish language, but had no role in study design, data collection and analysis, decision to publish or writing of the manuscript.
dc.relation.publisherversionhttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196152
dc.rightsAttribution 4.0 International*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subject.odsObjetivo 3: Salud
dc.titleMobility limitations related to reduced pulmonary function amongaging people with chronic obstructive pulmonary disease
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
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