Publication: Síndrome «humpy-backed» en cerdos en España
Authors
Pallarés Martínez, Francisco José ; Gómez, S. ; Pérez Marín, Mari Cruz ; Strickland, T ; García Nicolás, Olga ; Salguero, F.J. ; Seva Alcaraz, Juan
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Publisher
Murcia: Servicio de Publicaciones de la Universidad de Murcia
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DOI
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info:eu-repo/semantics/article
Description
Abstract
El síndrome «humpy-backed» fue descrito en cerdos por primera vez en el Reino Unido en 1984. El
síndrome ha sido observado en algunos países pero la etiología y la patogenia son todavía desconocidas. Este
caso describe la aparición de cerdos con «humpy-backed» en la lechonera de una granja de 3.800 cerdas situada
en el noreste de España. El problema afectó aproximadamente al 3% de la progenie semanal de una línea
genética particular de la granja compuesta por 450 cerdas. La incidencia alcanzó picos del 9-11% en algunas
semanas. Los lechones aparecían deprimidos, con pelaje hirsuto y deterioro físico progresivo. En la necropsia,
a pesar de la apariencia de lordosis, no se detectaron alteraciones en los huesos y articulaciones de la columna
vertebral. Microscópicamente se observó periarteritis linfoplasmocítica en corazón, bazo, intestino, hígado,
riñón, músculo esquelético, pulmón y meninges. También se observó miocarditis y miositis linfoplasmocítica
con degeneración de fibras musculares esqueléticas. La apariencia macroscópica de lordosis se relacionó
con infiltrado celular inflamatorio multiorgánico. Se asoció a un problema de tipo genético de los animales
afectados, aunque podría haber una posible implicación de circovirus porcino tipo 2 (PCV2) y el virus del
síndrome reproductivo y respiratorio porcino (PRRS) en la patogenia del síndrome, debido a la seropositividad
frente a los mismos detectada en la granja.
ABSTRACT: «Humpy-backed» pigs’ syndrome was firstly described in the United Kingdom in 1984. The syndrome has been reported in a few countries, but the ethiology and pathogenesis remains unclear. This report describes the appearance of «humpy-backed» piglets aetiology in the nursery of a 3800-sow farm in Northeast Spain. The problem affected around 3% of the weekly offspring from one particular genetic line present on the farm composed of 450 sows. The incidence reached peaks of 9-11% in some weeks. The piglets appeared depressed, with rough hair coat and progressive clinical deterioration. In the necropsy, despite the appearance of lordosis, no defect in the bones and joint of the vertebral spine were detected. Lympho-plasmacytic periarteritis was observed in heart, spleen, gut, liver, kidney, skeletal muscle, lung and meninges. Lympho-plasmacytic myocarditis and skeletal myositis with muscular fibre degeneration was also observed. The macroscopic appearance of lordosis was associated with a multiorganic inflammatory cell infiltration. There was an association with the genetic background of the affected animals although seropositivity to porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) was also found in the farm, pointing to a possible implication of viral infection in the pathogenesis of the syndrome.
ABSTRACT: «Humpy-backed» pigs’ syndrome was firstly described in the United Kingdom in 1984. The syndrome has been reported in a few countries, but the ethiology and pathogenesis remains unclear. This report describes the appearance of «humpy-backed» piglets aetiology in the nursery of a 3800-sow farm in Northeast Spain. The problem affected around 3% of the weekly offspring from one particular genetic line present on the farm composed of 450 sows. The incidence reached peaks of 9-11% in some weeks. The piglets appeared depressed, with rough hair coat and progressive clinical deterioration. In the necropsy, despite the appearance of lordosis, no defect in the bones and joint of the vertebral spine were detected. Lympho-plasmacytic periarteritis was observed in heart, spleen, gut, liver, kidney, skeletal muscle, lung and meninges. Lympho-plasmacytic myocarditis and skeletal myositis with muscular fibre degeneration was also observed. The macroscopic appearance of lordosis was associated with a multiorganic inflammatory cell infiltration. There was an association with the genetic background of the affected animals although seropositivity to porcine circovirus type 2 (PCV2) and porcine reproductive and respiratory syndrome virus (PRRSV) was also found in the farm, pointing to a possible implication of viral infection in the pathogenesis of the syndrome.
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