Publication: The growth of non-pyramidal neurons in the primary motor cortex of man: a Golgi study
Authors
Prinz, M. ; Prinz, B. ; Schulz, E.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
In Golgi-Cox-impregnated motor cortex
(regio precentralis) of six children (36 weeks of
gestation to 13 month after birth) four types of
interneurons of laminae 11-VI have been investigated
qualitatively and quantitatively and finally, compared
with interneurons of a child (3 month of age) with
Down's Syndrome. Al1 cell measurements have been
made by using a computerized digital morphometric
system. In order to study the developmental stage of
interneurons in our cases we statistically compared
analogue neuron types in the brains. As pararneters for
characterizing non-pyramidal neurons served the pattem
of dendritic branching, dendritic length for al1 dendritic
orders within single dendritic fields, and of the whole
neuron. The quantitative morphological study of
dendritic arborizations revealed that bitufted and large
multipolar intemeurons had significantly more branching
material in the postnatal brains than their prenatal
counterparts. These differences were due to the increase
of both length and number of branches during perinatal
period. Such constant increment in dendritic span and
branching provides larger receptive areas and that should
improve the development of connections in functional
intracortical columns. The quantitative parameter area of
dendritic fields and number of branching points of the
brain with Down's syndrome revealed in comparison
with normal brain of the same age differences such as
lower dendritic areas and a higher arnount of branching points
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