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Nuclear morphometry lacks prognostic value in squamous cell carcinoma of the oesophagus

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dc.contributor.authorRodriguez Sanjuan, J.C.es
dc.contributor.authorVal Bernal, F.es
dc.contributor.authorBlanco Garcia, C.
dc.contributor.authorGarcia-Castrillo Riesgo, L.
dc.date.accessioned2011-02-01T09:16:49Z
dc.date.available2011-02-01T09:16:49Z
dc.date.issued1993
dc.description.abstractIn order to determine the possible influence in oesophageal squamous cell carcinoma of nuclear measurements on patients' postoperative survival and on various histological tumour features, we performed a nuclear morphometry study on 53 patients (50 males, 3 females) with a mean age of 57.4 years (37-79). A statistical correlation was revealed between area, perimeter and diameter and the analysis was, therefore, performed only in terms of nuclear area. No influence of nuclear area on postoperative survival was observed. Nor was a relationship fourld between rnean nuclear area and either involvement of the oesophageal wall or degree of histological differentiation. The tumours showing expansive growth had a larger mean nuclear area than those of the infiltrative growth type, although differences did not reach statistical significance. The nuclear area standard deviation (reflecting anisocytosis of the tumour) showed no correlation with sllrvivill. In conclusion. our data do not support that measurement of nuclear parameters by static methods is of any prognostic value in surgically-treated squamous cell carcinoma of the oesophagus.es
dc.formatapplication/pdfes
dc.format.extent4es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18422
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectCarcinomaes
dc.subjectSquamous celles
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleNuclear morphometry lacks prognostic value in squamous cell carcinoma of the oesophaguses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 8, nº 3 (1993)