Publication: Evaluation of C-reactive-like protein in Mytilus galloprovincialis
Authors
Franco-Martínez, Lorena ; Tvarijonaviciute, Asta ; Mateo, Sandra V. ; Cerón, José J. ; Romero, Diego ; Oliveira, Miguel ; Teles, Mariana ; Martínez-Subiela, Silvia
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Publisher
Elsevier
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DOI
https://doi.org/10.1016/j.ecolind.2019.105537
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Description
©2019 Elsevier Ltd. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/. This document is the Published version of a Published Work that appeared in final form in Ecological Indicators. To access the final edited and published work see https://doi.org/10.1016/j.ecolind.2019.105537
Abstract
C-reactive protein (CRP) is an acute phase protein of the innate immune system with an important role as
biomarker in many biological processes in mammals. However, there is a lack of information regarding CRP in
molluscs and there is no data about the presence of CRP-like protein in mussels. In the present work, CPR-like
protein was identified and purified from the digestive gland of the Mediterranean mussel Mytilus galloprovincialis
In addition, it was demonstrated that CRP-like protein can be measured accurately and precisely by a high-
throughput automated method. Finally, higher levels of CRP-like protein in mussels exposed to hypoxia and
nanoplastics were detected when compared to controls. The results obtained indicate that CRP-like protein could be a suitable novel biomarker of inflammatory response in mussels for biomonitoring programs being economic, easy and rapid to determine.
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Citation
Ecological Indicators. Volume 106, November 2019, 105537
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Este ítem está sujeto a una licencia Creative Commons. http://creativecommons.org/licenses/by-nc-nd/4.0/