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Evaluation of C-reactive-like protein in Mytilus galloprovincialis

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dc.contributor.authorFranco-Martínez, Lorena
dc.contributor.authorTvarijonaviciute, Asta
dc.contributor.authorMateo, Sandra V.
dc.contributor.authorCerón, José J.
dc.contributor.authorOliveira, Miguel
dc.contributor.authorTeles, Mariana
dc.contributor.authorMartínez-Subiela, Silvia
dc.contributor.authorRomero García, Diego
dc.contributor.departmentCiencias Sociosanitarias
dc.date.accessioned2024-03-13T08:23:23Z
dc.date.available2024-03-13T08:23:23Z
dc.date.issued2019-07-05
dc.description©2019 Elsevier Ltd. All rights reserved. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/. This document is the Published version of a Published Work that appeared in final form in Ecological Indicators. To access the final edited and published work see https://doi.org/10.1016/j.ecolind.2019.105537es
dc.description.abstractC-reactive protein (CRP) is an acute phase protein of the innate immune system with an important role as biomarker in many biological processes in mammals. However, there is a lack of information regarding CRP in molluscs and there is no data about the presence of CRP-like protein in mussels. In the present work, CPR-like protein was identified and purified from the digestive gland of the Mediterranean mussel Mytilus galloprovincialis In addition, it was demonstrated that CRP-like protein can be measured accurately and precisely by a high- throughput automated method. Finally, higher levels of CRP-like protein in mussels exposed to hypoxia and nanoplastics were detected when compared to controls. The results obtained indicate that CRP-like protein could be a suitable novel biomarker of inflammatory response in mussels for biomonitoring programs being economic, easy and rapid to determine.es
dc.formatapplication/pdfes
dc.format.extent8es
dc.identifier.citationEcological Indicators. Volume 106, November 2019, 105537
dc.identifier.doihttps://doi.org/10.1016/j.ecolind.2019.105537
dc.identifier.issnPrint: 1470-160X
dc.identifier.issnElectronic: 1872-7034
dc.identifier.urihttp://hdl.handle.net/10201/140163
dc.languageenges
dc.publisherElsevieres
dc.relationPredoctoral contract ‘FPU’ of University of Murcia, Spain; Post-doctoral fellowship “Juan de la Cierva Incorporación” supported by the “Ministerio de Economía y Competitividad”, Spain; Post-doctoral fellowship from FCT (SFRH/BPD/109219/2015) supported by the European Social Fund and national funds from the“ Ministério da Educação e Ciência (POPH–QREN–Tipologia 4.1)” of Portugal; Program Investigador FCT, co-funded by the Human Potential Operational Programme and European Social Fund (IF/00335-2015).es
dc.relation.publisherversionhttps://www.sciencedirect.com/science/article/pii/S1470160X19305229?via%3Dihubes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectAcute phase responsees
dc.subjectBiomonitoringes
dc.subjectC-reactive proteines
dc.subjectHypoxiaes
dc.subjectPollutiones
dc.titleEvaluation of C-reactive-like protein in Mytilus galloprovincialises
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
relation.isAuthorOfPublicatione5600063-3079-4275-9892-ff8e48e3b96a
relation.isAuthorOfPublication.latestForDiscoverye5600063-3079-4275-9892-ff8e48e3b96a
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