Publication: Ewing's sarcoma of the cervix: a case report and review of literature.
Authors
Zhang, Yangyang ; Nong, Weixia ; Ren, Yan ; Jiang, Jinfang ; Zhang, Haijun ; Meng, Lian ; Li, Qianru ; Zhang, Qiaochu ; Wang, Xiaomeng ; Wang, Yang ; Liu, Chunxia ; Li, Feng
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Publisher
Universidad de Murcia, Departamento de Biologia Celular e Histiologia
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DOI
https://doi.org/10.14670/HH-18-181
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info:eu-repo/semantics/article
Description
Abstract
Ewing’s sarcoma (ES) is a small cell
malignant tumor that occurs in the bone of children or
adolescents. ES can also occur in extraskeletal organs,
such as the pancreas, thyroid, liver, proximal phalanx,
and, rarely, cervix. Only 15 published case reports have
discussed ES arising in the cervix. We report a 76-year-
old woman who had groin mass. ES was diagnosed in
accordance with morphological and immunohisto-
chemical maps. Fluorescence in situ hybridization and
RT-PCR (reverse transcription PCR) revealed ESWR1
gene rearrangement and fusion gene formation (EWS-
FLI-1), both of which confirmed the diagnosis of ES.
Although the patient underwent surgical resection, the
patient died without chemotherapy and radiotherapy.
This case is the first one to involve a patient aged over
70 years and the fifth one to show metastasis occurrence
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Citation
Histology and Histopathology Vol. 35, nº5 (2020)
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