Histology and histopathology Vol. 2, nº 3 (1987)
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- PublicationOpen AccessPrimary malignant melanoma of the nasal cavity, report of two cases and review of the literature(Murcia : F. Hernández, 1987) Sidoni, A.; Ottaviani, F.; Maurici, M.Primary malignant melanomas of the nasal cavity are rare, as only 400 cases have been reported to date. The present paper describes two cases recently seen in Caucasian women. The authors point out the difficult clinical diagnosis, as the symptoms are rather aspecific. From the histopathological point of view, diagnosis is easy in the melanotic cases while can show interpretating problems in the amelanotic ones, when melanoma is almost indistinguishable from other malignant neoplasms. A correlation between histological grading and prognosis was not detected, as both cases showed local recurrences within one year after surgery although they were, respectively, of epithelioid and indifferentiated type. While surgery appears to be the choice treatment of the primary lesion, the treatment of cervical metastasis is still disputable. On the whole, most authors think that the role played by radio- and mainly chemo-therapy is still limited and that cervical adenopathies should be treated by a simple lympho-adenectomy rather than by a neck dissection.
- PublicationOpen AccessSmooth muscle distribution in the capsule and trabeculae of the caprine superficial cervical lymph node(Murcia : F. Hernández, 1987) Faroon, O. M.; Henry, R. W.; Al-Bagdadi, F.K.This study centers around the dichotomy found in the literature concerning the presence of smooth muscle cells in the trabeculae and capsule of lymph nodes. Various superficial lymph nodes (mammary, mandibular, popliteal, subiliac, and superficial cervical) of the goat were collected and examined by light and electron microscopy. Smooth muscle cells were demonstrated in the capsule and trabeculae of lymph nodes independent of the blood and lymph vessels
- PublicationOpen AccessAssociation of sinus histiocytosis with massive lymphadenopathy and idiopathic hypereosinophilic syndrome(Murcia : F. Hernández, 1987) Hernández, Dimas; Gutierrez, Luis; Duque, Herminia; Olavarria, Renato; Muci, Rafael; Wunaii, HermanA patient was evaluated because of edema, pruritus and generalized painless lymphadenopathy. Laboratory tests showed marked eosinophilia without known etiology. CT scan of abdomen revealed multiple lymph nodes in retroperitoneal area. Lymph node biopsy was reported as sinus histiocytosis, bone marrow biopsy showed hipercellularity with marked infiltration of normal eosinophils. During his admission he developed Coombs positive hemolytic anaemia. Once he was stable, a laparotomy was performed and the patient died two days later because of septic shock. Autopsy revealed sinus histiocytosis with massive lymphadenopathy (SHML) with extranodal involvement of duodenum, spleen and prostate; septic liver and spleen, pyelonephritis, marked infiltration of eosinophilis in lymph nodes, spleen, liver duodenum and lungs. To the best of our knowledge, this is the first case report of the association of SHML and Idiopathic Hypereosinophilic Sundrome (HES) .
- PublicationOpen AccessRhabdomyoma of the soft palate. Fine structural details of a highly differentiated muscle tumor(Murcia : F. Hernández, 1987) Bock, D.; Böck, P.
- PublicationOpen AccessFat-rich diet induces inflammatory changes in the intact rat pancreas(Murcia : F. Hernández, 1987) Juhani Ramo, O.; Jalovaara, P.; Apaja-Sarkkinen, M.