Publication: Primary malignant melanoma of the nasal cavity, report of two cases and review of the literature
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Date
1987
Authors
Sidoni, A. ; Ottaviani, F. ; Maurici, M.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
Primary malignant melanomas of the nasal
cavity are rare, as only 400 cases have been reported to
date. The present paper describes two cases recently
seen in Caucasian women. The authors point out the
difficult clinical diagnosis, as the symptoms are rather
aspecific. From the histopathological point of view,
diagnosis is easy in the melanotic cases while can show
interpretating problems in the amelanotic ones, when
melanoma is almost indistinguishable from other malignant
neoplasms. A correlation between histological grading
and prognosis was not detected, as both cases showed
local recurrences within one year after surgery although
they were, respectively, of epithelioid and indifferentiated
type. While surgery appears to be the choice treatment of
the primary lesion, the treatment of cervical metastasis is
still disputable. On the whole, most authors think that
the role played by radio- and mainly chemo-therapy is
still limited and that cervical adenopathies should be
treated by a simple lympho-adenectomy rather than by a
neck dissection.
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