Browsing by Subject "Ventral prostate"

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    Androgen status and expression of glycoconjugates and lectins in the epithelial cells of the mouse ventral prostate. A glycohistochemical approach
    (Murcia : F. Hernández, 1994) Akif, F.; Gabius, H.J.; Danguy, A.
    We investigated histochemically the expression of glycans and endogenous sugar-binding proteins (endolectins) in the ventral prostate of normal and androgen-deprived mice. The avidin-biotinperoxidase complex technique was used with a panel of biotinylated lectins and neoglycoproteins, respectively, on paraffin sections. Characteristic binding patterns depending upon the type of lectin were observed in the glandular epithelium and basement membranes. This report also initiates the histochemical study of endogenous glycan-binding proteins in this maleaccessory sex organ. Remarkably, the endocrine status was found to affect the distribution of lectin-reactive determinants of glycoconjugates as well as endolectins. The histophysiological significance of these modifications in the glandular cells are discussed in the light of previous biochemical findings obtained mainly in humans and the rat.
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    Effects of melatonin, testosterone and the two hormones administered in parallel on ventral prostate of the rat treated with stilbestrol in the first day of life
    (Murcia : F. Hernández, 1995) Limanowski, A.; Miskowiak, B.; Otulakowski, B.
    Effects of melatonin, testosterone and the two hormones administered in parallel on ventral prostate were examined in the rats treated with estrogens in the first day of life. Thirty-nine-day long hormonal stimulation with melatonin, testosterone or the two hormones in parallel was started in rats aged 20, 28, 35 or 45 days. A single dose of estrogens led to atrophy of ventral prostate when the animals reached maturity, which was associated with high LH levels and low testosterone levels in the serum. Melatonin accentuated estrogen-induced changes in prostate morphology of ventral prostate while initemporal administration of melatonin and testosterone led to a resultant effect of testosterone-induced stimulation and melatonin-induced inhibition.