Browsing by Subject "Scar"

Now showing 1 - 2 of 2
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    La representación de la cicatriz en la poesía de Luna Miguel
    (Universidad de Murcia, Editum, 2019) Úbeda Sánchez, Patricia
    En el presente artículo se va a analizar la poesía de Luna Miguel a partir de la herida y la cicatriz, dos núcleos significativos de la poesía de esta poeta. Estos dos motivos e structuran el imaginario de la poeta. La importancia del cuerpo se enlaza con la búsqueda de la individualidad y la nostalgia de la infancia perdida. El cuerpo es el territorio en el que la voz poética inscribe la violencia, los impulsos más íntimos. La línea metodológica es interdisciplinar, en la que el cuerpo va a ser el objeto de estudio y cómo interviene en la escritura. El objetivo de este artículo es mostrar la escritura corpórea, teorizada por Hélène Cixous, se inscribe en la poesía migueliana mediante la herida y sus procesos de cicatricación con la finalidad de descubrir los mecanismos corpóreos de la escritura poética
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    The effect of bevacizumab, 5-fluorouracil, and triamcinolone on the healing modulation of surgical wounds in rats
    (Universidad de Murcia, Departamento de Biologia Celular e Histiologia, 2023) Simarro Rios, José Eduardo; Marques Almeida, Fábio; Murillo Limongi, Roberto; Souza Lino-Junior, Ruy de; Alves de Araújo, Lilhian; Pereira de Ávila, Marcos; Magacho, Leopoldo
    In this study, we aimed to analyze the effect of 5-fluorouracil, triamcinolone, and bevacizumab on scar modulation in an experimental rat model of surgical lesions. Rats (Rattus norvegicus albinus) were divided into four groups: bevacizumab, 5-fluorouracil + triamcinolone, bevacizumab + 5-fluorouracil + triamcinolone, and control (received no medication) groups. A linear, dorsal incision was created and sutured for the first intention wound healing, mimicking the surgical incision of upper blepharoplasty. Treatments were initiated on day 7, and the rats were euthanized on day 14. Only in the 5-fluorouracil + triamcinolone group was there a difference in the number of infiltrated monocytes. There was 56%, 86%, and 85% decrease in the number of neovessels in the bevacizumab, 5fluorouracil + triamcinolone, and bevacizumab + 5fluorouracil + triamcinolone groups, respectively, compared with the control. Picrosirius red staining showed higher collagen density and more organized collagen in the treatment groups than in the control group. Scar modulation was observed in all groups, but the 5-fluorouracil + triamcinolone group presented the best results. To our knowledge, this is the first study to evaluate the influence of three medications in combination on healing. When used together, these medications can prevent the development of unsightly scars, and are therefore promising alternatives to corticosteroids.