Browsing by Subject "Origin"

Now showing 1 - 4 of 4
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    CD34+ stromal cells/fibroblasts/fibrocytes/telocytes as a tissue reserve and a principal source of mesenchymal cells. Location, morphology, function and role in pathology
    (F. Hernández y Juan F. Madrid. Universidad de Murcia. Departamento de Biología Celular e Histología, 2014) Díaz-Flores, L.; Gutiérrez, R.; García, M. P.; Sáez, F.J.; Díaz-Flores Jr., L.; Valladares, F.; Madrid Cuevas, Juan Francisco
    We review the morphofunctional characteristics of CD34+ stromal fibroblastic/fibrocytic cells (CD34+ SFCs) and report our observations. We consider the following aspects of CD34+ SFCs: A) The confusing terms applied to this cell type, often combining the prefix CD34 with numerous names, including fibroblasts, fibrocytes, dendrocytes, keratocytes, telocytes and stromal, dendritic, adventitial, supraadventitial, perivascular, paravascular and delimiting cells; B) Changes in their immunophenotype, e.g., loss of CD34 expression and gain of other markers, such as those defining mesenchymal and derivate cells (myofibroblasts, osteoblasts, chondroblasts, adipocytes); C) Morphology (elongated or triangular cell body and thin, moniliform, bipolar or multipolar cytoplasmic processes), immunohistochemistry (co-expression of and changes in molecular expression) and structure (characteristics of nucleus and cytoplasmic organelles, and points of contact and junctions in quiescent and activated stages by light and electron microscopy); D) Location and distribution in the vessels (adventitia or external layer), in the tissues (connective, adipose, blood, muscle and nervous) and in the organs and systems (skin, oral cavity and oropharynx, respiratory, digestive, urinary, male, female, endocrine and lymphoid systems, serosal and synovial membranes, heart, eye and meninges); E) Origin from the mesoderm and cranial neural crest in the embryo, and from stem cells (themselves or other cells) and/or peripheral blood pluripotent stem cells (circulating progenitor cells) in post-natal life; F) Functions, such as synthesis of different molecules, progenitor of mesenchymal cells, immunomodulation, parenchymal regulation (growth, maturation and differentiation of adjacent cells), induction of angiogenesis, scaffolding support of other cells and phagocytic properties. Since CD34+ SFCs are the main reservoir of tissue mesenchymal cells (great mesenchymal potential, probably higher than that proposed for pericytes and other stromal cells), we dedicate a broad section to explain their in vivo behaviour during proliferation and differentiation in different physiologic and pathologic conditions, in addition to their characteristics in the human tissues of origin (adult stem cell niches); G) Involvement in pathological processes, e.g., repair (regeneration and repair through granulation tissue), fibrosis, tumour stroma formation and possible CD34+ SFC-derived tumours (e.g., solitary fibrous tumour, dermatofibrosarcoma protuberans, giant cell fibroblastoma, nuchal-type fibroma, mammary and extramammary myofibroblastoma, spindle and pleomorphic cell lipoma, and elastofibroma) and H) Clinical and therapeutic implications.
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    El descenso de las estrellas. El mundo originario y el origen del mundo en el pensamiento de J. Patočka
    (Universidad de Murcia. Servicio de Publicaciones, 2020) Garrido Maturano, Ángel Enrique
    El artículo analiza desde una perspectiva fenomenológica y hermenéutica el modo originario de donación del mundo y el origen del mundo en el pensamiento de Jan Patočka posterior a 1965. Primero muestra en qué sentido tanto la donación del mundo como horizonte, cuanto los movimientos de la existencia humana, implican un vínculo esencial entre el modo originario de darse del mundo y la noción de infinito, concebido como lo indefinido e inagotable. Finalmente explicita por qué el vínculo del mundo con lo infinito reposa sobre un impulso creativo divino que constituye el fundamento cosmológico de la religiosidad humana.
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    Los origenes y los motivos de la emigración China a México desde finales del siglo XIX hasta la década de 1940.
    (Universidad de Murcia, Servicio de Publicaciones., 2025) Zhou, Shenyu
    Objetivo de este artículo es el estudio de la emigración de china a México desde finales del siglo XIX hasta la década de 1940. Se aborda la cuantificación de los emigrantes, su origen geográfico, los motivos que les llevaron a emigrar, así como los que les llevaron a elegir México como país de destino. La emigración de chinos a México en la época contemporánea se inició en 1840, aunque fue a partir de 1870 cuando se produjo un progresivo incremento de emigrantes. La mayoría de ellos eran originarios de las provincias Guangdong y Fujian y los motivos que les impulsaron a dejar su país fueron tanto los problemas internos en China como los factores de atracción ejercida por México.
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    Pathological diagnosis, differential diagnosis and origin investigation of easily misdiagnosed adult gastric duplication cysts
    (Universidad de Murcia, Departamento de Biologia Celular e Histiologia, 2022) Liu, Fangfang; Zhao, Huimin
    Objectives. To study diagnosis, differential diagnosis, and origin of easily misdiagnosed adult gastric duplication cysts. Methods. Six cases with GDCs were studied using immunohistochemical methods to research the expression of tumor markers. Results. Most GDCs were located in the abdominal cavity outside the digestive organs. The cyst wall tissues included a repetition of the full-thickness structure of the stomach wall that was lined by a variety of different epithelia. The expression of CK7 was positive in all epithelia (6/6), while CK7 expression was positive in cardia glands in 5/5 and positive in fundus glands in 1/5. CK 20 was 100% (4/4) positively expressed in the SCE, 100% (3/3) negative in the CCE, and in the SE. It was also expressed positively 100% (5/5) in fundus glands and 80% (4/5) in cardia glands. Both CK7 and CK20 were negatively expressed in the pyloric glands in case 3. The expression of MUC1 was positive in all epithelia and glands, whereas MUC2 expression was negative. MUC5AC was expressed differently in epithelia and glands. Conclusions. GDCs can originate from the antrum or the fundus of the stomach. Tumor markers can help diagnosis and differential diagnosis. This study may help to improve clinical precision treatment.