Vacuolar-type proton pump ATPases: Acidification and pathological relationships

Sun-Wada, Ge-Hong; Wada, Yoh

Publication:
Vacuolar-type proton pump ATPases: Acidification and pathological relationships

dc.contributor.author	Sun-Wada, Ge-Hong
dc.contributor.author	Wada, Yoh
dc.date.accessioned	2018-06-21T13:56:57Z
dc.date.available	2018-06-21T13:56:57Z
dc.date.issued	2013
dc.description.abstract	Vacuolar H + -translocating ATPase (V- ATPase) is a universal proton pump, and its activity is required for a variety of cell biological processes, such as membrane trafficking, receptor-mediated endocytosis, lysosomal degradation of macromolecules, osteoclastic bone resorption, and the maintenance of acid-base homeostasis by renal intercalated cells. V-ATPase is targeted to various membranes and has different compositions depending on its cellular location. Here, we focus on recent knowledge concerning the targeting mechanism of V-ATPase, a process associated with a wide spectrum of diseases. We also discuss the functions of this enzyme in macrophages and cancer	es
dc.format	application/pdf	es
dc.format.extent	11	es
dc.identifier.citation	Histology and histopathology, Vol. 28, n.º 7 (2013)
dc.identifier.issn	1699-5848
dc.identifier.issn	0213-3911
dc.identifier.uri	http://hdl.handle.net/10201/59540
dc.language	eng	es
dc.publisher	F. Hernández y Juan F. Madrid. Universidad de Murcia. Departamento de Biología Celular e Histología	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.subject	V-ATPase	es
dc.subject	Acidification	es
dc.subject.other	CDU::5 - Ciencias puras y naturales::57 - Biología::576 - Biología celular y subcelular. Citología	es
dc.title	Vacuolar-type proton pump ATPases: Acidification and pathological relationships	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es