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The MUC gene family, Their role in the diagnosis and prognosis of gastric cancer

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dc.contributor.authorSenapati, Shantibhusanes
dc.contributor.authorSharma, Poonames
dc.contributor.authorBafna, Sangeeta
dc.contributor.authorRoy, Hemant K.
dc.contributor.authorBatra, Surinder K.
dc.date.accessioned2013-01-18T13:44:51Z
dc.date.available2013-01-18T13:44:51Z
dc.date.issued2008
dc.description.abstractEarly diagnosis of gastric cancer and its differential diagnosis from other non-malignant gastric diseases like gastritis is still a major clinical problem. Most patients are asymptomatic in the early stages of gastric cancer, and there is no reliable marker available for the early and specific diagnosis of gastric cancer. Many attempts have been made to define the biological profile of gastric cancer to improve the chances of its early diagnosis, prognosis and treatment. Several studies have shown the aberrant expression profile of mucins in different malignancies, suggesting that mucins have a great potential to be used as a diagnostic and prognostic marker in gastric cancer. In this review, we have briefly described the different types of gastric adenocarcinomas and the progression of gastric cancer. Furthermore, the role of mucins and their related carbohydrate epitope is discussed in the normal stomach and in the diagnosis and prognosis of gastric adenocarcinomas.es
dc.formatapplication/pdfes
dc.format.extent12es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/29727
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectGastric canceres
dc.subjectDiagnosises
dc.subject.other616.3 - Patología del aparato digestivo. Odontologíaes
dc.titleThe MUC gene family, Their role in the diagnosis and prognosis of gastric canceres
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.23,nº12 (2008)