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Jacalin, another marker for histiocytes in paraffin-embedded tissues

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dc.contributor.authorUrdiales Viedma, M.es
dc.contributor.authorDe Haro Muñoz, T.es
dc.contributor.authorMartos Padilla, S.
dc.contributor.authorAbad Ortega, J.M.
dc.contributor.authorVarela Durán, J.
dc.contributor.authorGranda Paez, R.
dc.date.accessioned2011-02-22T10:30:41Z
dc.date.available2011-02-22T10:30:41Z
dc.date.issued1995
dc.description.abstractJacalin is a lectin which reacts with Dgalactose. We have tested jacalin on 75 samples of different formalin- and alcohol-fixed tissues. A consistent cytoplasmic stain of the histiocytes was observed in paraffin-embedded tissues in al1 cases studied of reactive sinus histiocytosis, macrophages in clear centres of follicular hyperplasia, in tuberculosis granulomas and in osteoclast-like giant cells in a breast carcinoma. We failed to find any clear binding of jacalin to the cells of eosinophilic granulomas, giant cell tumors of tendon sheath, pleomorphic malignant fibrous histiocytomas, Hodgkin's disease, melanomas, nevi or signet ring cell carcinomas of the breast and stomach. It seems that jacalin is a good marker for free histiocytesl macrophages, not for fixed histiocytes and tumors related to them. This lectin might play a role in differential diagnosis with histiocyte mimicking processes.es
dc.formatapplication/pdfes
dc.format.extent6es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18750
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectHistiocyteses
dc.subjectMacrophageses
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titleJacalin, another marker for histiocytes in paraffin-embedded tissueses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.10, nº 3 (1995)