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Neurobiological toxicity of radiation in hippocampal cells

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dc.contributor.authorKim, Joong-Sun
dc.contributor.authorYang, Miyoung
dc.contributor.authorKim, Sung-Ho
dc.contributor.authorShin, Taekyun
dc.contributor.authorMoon, Changjong
dc.date.accessioned2018-02-15T18:39:36Z
dc.date.available2018-02-15T18:39:36Z
dc.date.issued2013
dc.description.abstractWorldwide radiation exposure is increasing due to recent nuclear accidents, space travel, atomic weapons testing and use, and medical treatments. In adult animals, ionizing radiation can significantly impact hippocampal neurogenesis and negatively affect hippocampal functions such as cognition. However, there is considerable uncertainty regarding the mechanisms underlying these effects. This article reviews in vivo and in vitro studies on the effects of irradiation on hippocampal neurogenesis and function in order to gain new mechanistic insights. This information will provide complementary views of our understanding of the normal brain’s tolerance to radiation exposure, the potentially serious implications of radiation exposure to cognition, and lead to a discussion of potential strategies for pharmacotherapy and behavioral intervention.es
dc.formatapplication/pdfes
dc.format.extent10es
dc.identifier.citationHistology and histopathology, Vol. 28, n.Âş 3 (2013)
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/56137
dc.languageenges
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectCognitiones
dc.subjectRadiationes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::615 - Farmacología. Terapéutica. Toxicología. Radiologíaes
dc.titleNeurobiological toxicity of radiation in hippocampal cellses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.28, nÂş 3 (2013)