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Lectin histochemistry of human meningiomas

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dc.contributor.authorMarafioti, T.es
dc.contributor.authorBarresi, G.es
dc.contributor.authorBatolo, D.
dc.date.accessioned2011-02-01T09:18:08Z
dc.date.available2011-02-01T09:18:08Z
dc.date.issued1994
dc.description.abstractThe lectins Peanut agglutinin (PNA), Canavalia ensiformis (Con A), Ulex europaeusl (UEAl), Dolichos biflorus (DBA), Triticum vulgaris (WGA) were studied in a series of 36 meningiomas (16 meningotheliomatous-including 3 recurrences, 7 transitional, 4 angiomatous, 2 ((hemangiopericytic~3, papillary-including 1 recurrence, 4 anaplastic-including 3 recurrences. PNA binds to all cases of meningotheliomatous, transitional, papillary and anaplastic meningiomas (including recurrent cases) but the staining is more intense in tumor cells of anaplastic and papillary type. A semiquantitative study showed differences of PNAreactivity in the different subtypes of meningiomas. In meningotheliomatous meningiomas PNA-positivity was encountered in numerous neoplastic cells (50%), whereas papillary and anaplastic subtypes expressed strong cytoplasmic staining of few tumor cells (C 5%). Con A shows the same pattern of reactivity described for PNA, but more weakly. Our results suggest that PNA is a marker of differentiation in meningiomas rather than malignant transformation and can have prognostic relevance.es
dc.formatapplication/pdfes
dc.format.extent6es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18503
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectLectines
dc.subjectMeningiomaes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleLectin histochemistry of human meningiomases
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 9, nº 3 (1994)