Chromatin in embryonic stem cell neuronal differentiation

Publication:
Chromatin in embryonic stem cell neuronal differentiation

dc.contributor.author	Meshorer, E.	es
dc.date.accessioned	2012-05-21T12:09:05Z
dc.date.available	2012-05-21T12:09:05Z
dc.date.issued	2007
dc.description.abstract	Chromatin, the basic regulatory unit of the eukaryotic genetic material, is controlled by epigenetic mechanisms including histone modifications, histone variants, DNA methylation and chromatin remodeling. Cellular differentiation involves large changes in gene expression concomitant with alterations in genome organization and chromatin structure. Such changes are particularly evident in self-renewing pluripotent embryonic stem cells, which begin, in terms of cell fate, as a tabula rasa, and through the process of differentiation, acquire distinct identities. Here I describe the changes in chromatin that accompany neuronal differentiation, particularly of embryonic stem cells, and discuss how chromatin serves as the master regulator of cellular destiny.	es
dc.format	application/pdf	es
dc.format.extent	9	es
dc.identifier.issn	0213-3911	es
dc.identifier.uri	http://hdl.handle.net/10201/27563
dc.language	eng	es
dc.publisher	Murcia : F. Hernández	es
dc.relation.ispartof	Histology and histopathology	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.subject	Chromatin	es
dc.subject	Neurons	es
dc.subject.other	616.8 - Neurología. Neuropatología. Sistema nervioso	es
dc.title	Chromatin in embryonic stem cell neuronal differentiation	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es

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