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Salivary adiponectin, but not adenosine deaminase, correlates with clinical signs in women with Sjögren's syndrome: a pilot study

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dc.contributor.authorLópez Jornet, María Pía
dc.contributor.authorTvarijonaviciute, Asta
dc.contributor.authorZamora, Carmen
dc.contributor.authorMartinez Subiela, Silvia
dc.contributor.authorTecles, Fernando
dc.contributor.authorPina, Francisca
dc.contributor.departmentDermatología, Estomatología, Radiología y Medicina Física
dc.date.accessioned2024-01-30T11:29:37Z
dc.date.available2024-01-30T11:29:37Z
dc.date.issued2019-03
dc.description.abstractAbstract Objectives: To evaluate salivary adiponectin and adenosine deaminase (ADA) in women suffering from Sjögren's syndrome (SS). Methods: Salivary adiponectin and ADA were measured in patients with SS (n = 17) and compared to their values in healthy controls (n = 13) and patients suffering from drug-induced xerostomia (non-SS sicca group; n = 19). A clinical history was made for each patient, patients were examined clinically, and xerostomia inventory (XI) was performed. Results: Salivary adiponectin corrected by total protein was higher in patients with SS than in healthy individuals (P < 0.05) or patients with non-SS sicca (P < 0.01) and correlated with XI (r = 0.555; P < 0.05). Salivary ADA was higher in patients with SS and non-SS sicca compared to controls (P < 0.05 in both cases). Conclusion: The results of the present study indicate that adiponectin and ADA are increased in the saliva of patients with SS. Clinical relevance: Salivary adiponectin corrected by total protein can be a potential biomarker of SS. Trial registration: NCT03156569.es
dc.formatapplication/pdfes
dc.identifier.citationClinical Oral Investigations
dc.identifier.doi10.1007/s00784-018-2570-3
dc.identifier.issn1432-6981
dc.identifier.issn1436-3771
dc.identifier.urihttp://hdl.handle.net/10201/138135
dc.languageenges
dc.relationSin financiación externa a la Universidades
dc.rights.accessRightsinfo:eu-repo/semantics/restrictedAccess
dc.subjectAdenosine deaminasees
dc.subjectAdiponectines
dc.subjectBiomarkeres
dc.subjectClinical signses
dc.subjectSalivaes
dc.subjectXerostomiaes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleSalivary adiponectin, but not adenosine deaminase, correlates with clinical signs in women with Sjögren's syndrome: a pilot studyes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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