Publication: Sex moderates the relationship of stress and perceived social support with neuropsychological symptoms
among community-dwelling persons with Alzheimer disease in Spain
Authors
Gallego Mellado, María ; Gómez Gallego, Juan Cándido ; Gómez García, Juan
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Publisher
Lippincott, Williams & Wilkins
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DOI
https://doi.org/: 10.1097/WAD.0000000000000416.
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info:eu-repo/semantics/article
Description
© 2020 Wolters Kluwer Health, Inc. This document is the Published version of a Published Work that appeared in final form in Alzheimer Disease and Associated Disorders. To access the final edited and published work see https://doi.org/: 10.1097/WAD.0000000000000416
Abstract
Abstract: Neuropsychiatric symptoms (NPS) are common in Alz heimer disease (AD) patients, especially in women. Stress and stress vulnerability factors (eg, poor social support) may trigger NPS. This
cross-sectional study (n=196) aimed to examine the moderating effect
of sex on the relationships between both perceived social support and
salivary cortisol levels and NPS of AD patients. Only in women,
greater cortisol levels were associated with higher scores in Neuro psychiatric Inventory mood, agitation, and frontal subscales whereas
higher Psychosocial Support Questionnaire scores were related to
lower scores in Neuropsychiatric Inventory mood and psychosis
subscales. Given the relevance that sex differences might have on the
design of preventive strategies, present findings should be confirmed in
longitudinal studies
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Citation
Alzheimer Disease and Associated Disorders, 2021 (Octubre-Diciembre), Vol. 35, Number 4, pp. 353-355
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