Publication:
Emergence of cfr-Mediated Linezolid Resistance in a Methicillin-Resistant Staphylococcus aureus Epidemic Clone Isolated from Patients with CysticFibrosis

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dc.contributor.authorde Dios Caballero, J
dc.contributor.authorPastor, MD
dc.contributor.authorVindel, A
dc.contributor.authorMáiz, L
dc.contributor.authorYagüe, G
dc.contributor.authorSalvador, C
dc.contributor.authorCobo, M
dc.contributor.authorMorosini, MI
dc.contributor.authordel Campo, R
dc.contributor.authorCantón, R
dc.contributor.departmentGenética y Microbiología
dc.date.accessioned2024-01-30T09:07:13Z
dc.date.available2024-01-30T09:07:13Z
dc.date.issued2015-12
dc.description.abstractResistance to linezolid (LZD) in methicillin-resistant Staphylococcus aureus (MRSA) isolates from patients with cystic fibrosis (CF) is due mainly to ribosomal mutations. We report on four CF patients with LZD-resistant MRSA bronchopulmonary infections by strains carrying the cfr gene. Strains from one patient also harbored the G2576U mutation (23S rRNA) and the G139R substitution (L3 protein). All strains belonged to the epidemic clone ST125 MRSA IVc. Our results support the monitoring of LZD resistance emergence in CF and non-CF MRSA isolateses
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dc.identifier.citationAntimicrob Agents Chemother. 2015. 60(3):1878-82
dc.identifier.doihttps://doi.org/10.1128/aac.02067-15
dc.identifier.issn0066-4804
dc.identifier.issn1098-6596
dc.identifier.urihttp://hdl.handle.net/10201/138122
dc.languageenges
dc.relationSin finaciación externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectcfr-mediated linezolid resistance cystic fibrosises
dc.titleEmergence of cfr-Mediated Linezolid Resistance in a Methicillin-Resistant Staphylococcus aureus Epidemic Clone Isolated from Patients with CysticFibrosises
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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