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New aspects on the role of lipoxygenases in cancer progression

dc.contributor.authorCatalano, A.es
dc.contributor.authorProcopio, A.es
dc.date.accessioned2011-06-30T12:00:57Z
dc.date.available2011-06-30T12:00:57Z
dc.date.issued2005
dc.description.abstractThe Lipoxygenases (LOXs) are a class of enzymes that convert arachidonic, linoleic, and other polyunsaturated fatty acid into biologically active metabolites involved in the inflammatory and immune responses. Recent evidences indicate that LOXs and the signaling pathways that are involved in their activation are also important for carcinogenesis and tumor progression. LOXs should therefore receive as much attention from cancer researchers as it has already from immunologists. In this article, we will review some evidence that the LOXs pathways affect several aspects of lung, pancreatic and prostate cancer progression. Moreover, we discuss how this new perspective on the roles of LOXs and their metabolites can have important implications to cancer therapy.es
dc.formatapplication/pdfes
dc.format.extent7es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/22530
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectLunges
dc.subjectPancreases
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleNew aspects on the role of lipoxygenases in cancer progressiones
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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