Publication:
Renal leiomyoma: An immunohistochemical, ultrastructural and comparative genomic hybridization study

dc.contributor.authorKuroda, Naotoes
dc.contributor.authorInoue, Y.es
dc.contributor.authorTaguchi, T.
dc.contributor.authorTominaga, A.
dc.contributor.authorHes, O.
dc.contributor.authorMichal, Michal
dc.contributor.authorHayashi, Yoshihiro
dc.contributor.authorHiroi, Makoto
dc.contributor.authorShuin, T.
dc.contributor.authorLee, Gang-Hong
dc.date.accessioned2012-05-21T12:10:28Z
dc.date.available2012-05-21T12:10:28Z
dc.date.issued2007
dc.description.abstractRenal leiomyoma is a rare neoplasm. We report such a case in a 57-year-old Japanese woman who was found to have a mass in the left kidney. The histological examination disclosed the proliferation of spindle cells showing a benign appearance. Entrapped tubular cells were observed in the peripheral area of the tumor. The immunohistochemical examination of spindle neoplastic cells showed a positive reaction for alpha smooth muscle actin, h-caldesmon, l-caldesmon, calponin, muscle actin, myosin and desmin. Additionally, the ultrastructural examination of the tumor showed membrane caveolae and myofilaments in the cytoplasm. This tumor was considered to show a differentiation into smooth muscle cells. The comparative genomic hybridization of the tumor detected the combined losses of chromosomes 4, 6, 12 and 14 which has not been previously described in renal tumors. Finally, the immunohistochemical panel of smooth muscle markers and ultrastructural and genetic study may be useful in diagnosing renal leiomyoma.es
dc.formatapplication/pdfes
dc.format.extent6es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/27615
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectRenal leiomyomaes
dc.subjectImmunohistochemistryes
dc.subject.other616.6 - Patología del sistema genitourinarioes
dc.titleRenal leiomyoma: An immunohistochemical, ultrastructural and comparative genomic hybridization studyes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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