Publication: The multiple facets of the club cell in the pulmonary epithelium
Authors
López Valdez, Nelly ; Rojas Lemus, Marcela ; Bizarro-Nevares, Patricia ; González Villalva, Adriana Elizabeth ; Casarrubias Tabarez, Brenda ; Cervantes Valencia, María Eugenia ; Ustarroz-Cano, Martha ; Morales Ricardes, Guadalupe ; Mendoza Martínez, Shamir ; Guerrero Palomo, Gabriela ; Fortoul, Teresa I.
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Publisher
Universidad de Murcia, Departamento de Biologia Celular e Histiologia
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DOI
https://doi.org/10.14670/HH-18-713
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info:eu-repo/semantics/article
Description
Abstract
The non-ciliated bronchiolar cell, also referred to as “club cell”, serves as a significant multifunctional component of the airway epithelium. While the club cell is a prominent epithelial type found in rodents, it is restricted to the bronchioles in humans. Despite these differences, the club cell's importance remains undisputed in both species due to its multifunctionality as a regulatory cell in lung inflammation and a stem cell in lung epithelial regeneration.
The objective of this review is to examine different aspects of club cell morphology and physiology in the lung epithelium, under both normal and pathological conditions, to provide a comprehensive understanding of its importance in the respiratory system.
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Citation
Histology and Histopathology Vol. 39, nº8 (2024)
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