Publication:
Advances in the knowledge of breast cancer stem cells. A review

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Schwarz-Cruz-31-601-612-2016.pdf(213.21 KB)
Date
2016
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Authors
Schwarz-Cruz y Celis, Angela ; Espinosa, Magali ; Maldonado, Vilma ; Melendez-Zajgla, Jorge
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Publisher
Universidad de Murcia. Departamento de Biología Celular e Histología
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DOI
DOI:10.14670/HH-11-718
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info:eu-repo/semantics/article
Description
Abstract
Much effort has been made by researchers to elucidate the complex biology of breast cancer stem cells (BCSCs), a small subset of breast tumor cells that display stem cell properties, drive tumor initiation, and growth. In recent years, it has been suggested that BCSCs could be responsible for the process of metastasis and the development of drug resistance. These findings make the need to find the distinguishing blend of markers that can recognize only BCSCs of the utmost importance in order to be able to design new targeted therapies. This review will summarize BCSCs’ main features as well as the cell surface markers that are currently used to identify them.
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Breast cancer , Cancer stem cells , Breast cancer stem cells , Markers , Therapeutic resistance
Citation
Histology and histopathology: Vol.31, nº6 (2016)
URI
http://hdl.handle.net/10201/111244
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Histology and histopathology Vol.31, nº6 (2016)
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