Publication: Clinical management of the homozygous α-thalassemia with unusual mandibular manifestation of hematopoiesis
Authors
Ruiz Roca, Juan Antonio ; Oñate Sánchez, Ricardo Elías ; Urrutia Rodríguez, Idoia ; Martínez-Izquierdo, A. ; Mengual-Pujante, D. ; Rodríguez Lozano, Francisco Javier
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Facultad de Medicina
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Publisher
Elsevier
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DOI
https://doi.org/10.1016/j.jormas.2016.12.007
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info:eu-repo/semantics/article
Description
Abstract
Alpha (α)-thalassemias are the most common genetic disorder of hemoglobin (Hb) synthesis, affecting up to 5% of the world's population. These congenital hemolytic anemias induce extramedullary hematopoiesis, including the liver, spleen, sinuses, and the diploic spaces of the skull. Oral health problems in patients with thalassemias are mostly related to a varied degree of facial deformities, malocclusions, and/or dental arch dimensions. We present a case with a 49-year-old man, diagnosed with homozygous α thalassemia that came to the Faculty of Dentistry at the University of Murcia for a dental treatment. It was observed that the patient had an unusual mandibular manifestation of hematopoiesis.
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Citation
J Stomatol Oral Maxillofac Surg 118 (2017) 49–51
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