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Age-related morphometric changes occurring in the somata of astrocytes of the granular layer of rat neocerebellar cortex (Crus I and Crus II)

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dc.contributor.authorMonteiro, R.A.F.es
dc.contributor.authorRocha, E.es
dc.contributor.authorMarini-Abreu, M.M.
dc.date.accessioned2011-02-01T08:47:36Z
dc.date.available2011-02-01T08:47:36Z
dc.date.issued1992
dc.description.abstractA quantitative study conceming the agerelated changes occurring in the cell body and somatic organelles of neocerebellar astrocytes is carried out, using rats aged 2 to 24 months. Manual stereological techniques are used to determine the following parameters on electron micrographs: the somatic volume, the volume density and the absolute volume of the protoplasmic structures as well as the mean surface of the rough endoplasmic reticulum cisternae per cell.None of the pararneters reveals any clear-cut general temporal pattern. The soma and the cell components show statistically significant differences in the parameters with ageing, excepting the dense bodies (relative and absolute volumes) and the Golgi apparatus (relative volume). There are significant positive linear trends between, on the one hand, the somatic volume and, on the other hand, the absolute volume of either of the following structures: nucleus, glial filaments, ground substance and dense bodies. Some linear correlations between the absolute volumes of organelles are also found. Despite the ability for karyokinesis, it is concluded that astrocytes do undergo changes with ageing.es
dc.formatapplication/pdfes
dc.format.extent18es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18338
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectMorphometryes
dc.subjectAstrocyteses
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleAge-related morphometric changes occurring in the somata of astrocytes of the granular layer of rat neocerebellar cortex (Crus I and Crus II)es
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 7, nº 3 (1992)