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Clinical and pathological features of osteosarcomas of the jaws: a retrospective study

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dc.contributor.authorRodriguez-Molinero, Jesús
dc.contributor.authorPozo-Kreilinger, José Juan
dc.contributor.authorRuiz Roca, Juan Antonio
dc.contributor.authorLópez-Sánchez, Antonio Francisco
dc.contributor.authorCebrian-Carretero, José Luis
dc.contributor.departmentDermatología, Estomatología, Radiología y Medicina Física
dc.contributor.otherFacultad de Medicina
dc.date.accessioned2026-03-24T08:45:58Z
dc.date.available2026-03-24T08:45:58Z
dc.date.copyright© 2024 by the authors
dc.date.issued2024-05-23
dc.description.abstractIntroduction: Osteosarcomas of the jaw (OSJs) are rare tumors with distinct characteristics from osteosarcomas affecting other bones. This study aims to analyze the clinical, pathological, and therapeutic characteristics of OSJs. Methods: A retrospective, descriptive cross-sectional study including patients diagnosed with OSJ registered at the “La Paz” University Hospital, Madrid, was performed. Results: Data of eight patients with a diagnosis of OSJ were obtained during the study period of 22 years (2002–2024). The mean age of the patients was 41 years. The distribution was 1:1 between the maxilla andmandible. Painful inflammation asthemostfrequentclinical manifestation. Conventional osteoblastic osteosarcoma was the most predominant histological type. Survival rate at 5 years was 50%, which decreased to 25% at 10 years. Conclusions: OSJs differ from conventional osteosarcomas of long tubular bones. Surgery continues to be the mainstay of treatment. However, more studies are needed through which more standardized protocols can be proposed for adjuvant therapeutic management.
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dc.identifier.citationRodriguez-Molinero J, Pozo-Kreilinger JJ, Ruiz-Roca JA, Lopez-Sanchez AF, Cebrian-Carretero JL. Clinical and Pathological Features of Osteosarcomas of the Jaws: A Retrospective Study. Clin Pract. 2024 May 23;14(3):965-979. doi: 10.3390/clinpract14030077
dc.identifier.doihttps://doi.org/10.3390/clinpract14030077
dc.identifier.eissn2039-7283
dc.identifier.urihttp://hdl.handle.net/10201/222541
dc.languageeng
dc.publisherMDPI
dc.relationSin financiación externa a la Universidad
dc.relation.publisherversionhttps://www.mdpi.com/2039-7283/14/3/77
dc.rightsAttribution 4.0 International*
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/*
dc.subjectHead and neck cancer
dc.subjectOral cancer
dc.subjectMalignant bone tumors
dc.subjectOsteosarcoma of the jaw
dc.subject.odsNo relacionado con ningún objetivo de desarrollo sostenible
dc.titleClinical and pathological features of osteosarcomas of the jaws: a retrospective study
dc.typeinfo:eu-repo/semantics/article
dc.type.versioninfo:eu-repo/semantics/publishedVersion
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relation.isAuthorOfPublicatione24de175-ae66-43d3-adbd-c15f9022e2b6
relation.isAuthorOfPublication.latestForDiscoverye24de175-ae66-43d3-adbd-c15f9022e2b6
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