Publication: Clinical and pathological features of osteosarcomas of the jaws: a retrospective study
Authors
Rodriguez-Molinero, Jesús ; Pozo-Kreilinger, José Juan ; Ruiz Roca, Juan Antonio ; López-Sánchez, Antonio Francisco ; Cebrian-Carretero, José Luis
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Facultad de Medicina
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Publisher
MDPI
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DOI
https://doi.org/10.3390/clinpract14030077
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info:eu-repo/semantics/article
Description
Abstract
Introduction: Osteosarcomas of the jaw (OSJs) are rare tumors with distinct characteristics from osteosarcomas affecting other bones. This study aims to analyze the clinical, pathological, and therapeutic characteristics of OSJs. Methods: A retrospective, descriptive cross-sectional study including patients diagnosed with OSJ registered at the “La Paz” University Hospital, Madrid, was performed. Results: Data of eight patients with a diagnosis of OSJ were obtained during the study period of 22 years (2002–2024). The mean age of the patients was 41 years. The distribution was 1:1 between the maxilla andmandible. Painful inflammation asthemostfrequentclinical manifestation. Conventional osteoblastic osteosarcoma was the most predominant histological type. Survival rate at 5 years was 50%, which decreased to 25% at 10 years. Conclusions: OSJs differ from conventional osteosarcomas of long tubular bones. Surgery continues to be the mainstay of treatment. However, more studies are needed through which more standardized protocols can be proposed for adjuvant therapeutic management.
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Citation
Rodriguez-Molinero J, Pozo-Kreilinger JJ, Ruiz-Roca JA, Lopez-Sanchez AF, Cebrian-Carretero JL. Clinical and Pathological Features of Osteosarcomas of the Jaws: A Retrospective Study. Clin Pract. 2024 May 23;14(3):965-979. doi: 10.3390/clinpract14030077
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