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Neuromedins and their involvement in the regulation of growth, structure and function of the adrenal cortex

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dc.contributor.authorMalendowicz, L.K.es
dc.contributor.authorMarkowska, A.es
dc.date.accessioned2011-02-01T09:18:13Z
dc.date.available2011-02-01T09:18:13Z
dc.date.issued1994
dc.description.abstractCurrent data on the synthesis and the mechanism of action of neuromedins on adrenal cortex are presented. The localization of these biologicallyactive peptides in all components of the hypothalamopituitary- adrenal axis as well as their action on the adrenal cortex both in vivo and in vitro suggest their involvement in the regulation of growth, structure and function of the adrenal cortex. Neuromedins may exert both direct and indirect effect on the adrenal cortex. Direct effect is proven by the stimulation of glucocorticoid synthesis by adrenocortical cells in culture (NMK, NML) while indirect effects may be mediated by ACTH, vasopressin (aldosterone secretagogue effect) and angiotensin (prompt proliferative response) or by substances of medullary origin. The last mechanism of action is well documented for NMU.es
dc.formatapplication/pdfes
dc.format.extent11es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18509
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectHypothalamuses
dc.subjectPituitaryes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleNeuromedins and their involvement in the regulation of growth, structure and function of the adrenal cortexes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 9, nº 3 (1994)