New insights into the cytoplasmic function of PML

Publication:
New insights into the cytoplasmic function of PML

dc.contributor.author	Salomoni, P.	es
dc.contributor.author	Bellodi, C.	es
dc.date.accessioned	2012-05-21T12:10:33Z
dc.date.available	2012-05-21T12:10:33Z
dc.date.issued	2007
dc.description.abstract	PML is a tumour suppressor inactivated in Acute Promyelocytic Leukaemia (APL). PML is the essential component of a subnuclear structure called the PML nuclear body (PML-NB), which is disrupted in APL. By targeting different cellular proteins to this structure, PML can either hamper or potentiate their functions. The PML transcript undergoes alternative splicing to generate both nuclear and cytoplasmic isoforms. Most of the research in this field has focused its attention on studying nuclear PML. Nevertheless, new exciting studies show that cytoplasmic PML may control essential cellular functions, thus opening new avenues for investigation.	es
dc.format	application/pdf	es
dc.format.extent	10	es
dc.identifier.issn	0213-3911	es
dc.identifier.uri	http://hdl.handle.net/10201/27619
dc.language	eng	es
dc.publisher	Murcia : F. Hernández	es
dc.relation.ispartof	Histology and histopathology	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.subject	Viral infection	es
dc.subject	Tumours	es
dc.subject.other	615 - Farmacología. Terapéutica. Toxicología. Radiología	es
dc.title	New insights into the cytoplasmic function of PML	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es

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