Publication: Role of cytokines in host defense against Staphylococcus aureus skin infection
Authors
Wu, Guosheng ; Zhu, Banghui ; Hong, Xudong ; Luo, Pengfei ; Xia, Zhaofan
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Publisher
Universidad de Murcia. Departamento de BiologĂa Celular e HistologĂa
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DOI
DOI: 10.14670/HH-11-867
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info:eu-repo/semantics/article
Description
Abstract
Wound infection caused by Staphylococcus
aureus (S. aureus) is a critical clinical problem due to
long hospitalization times, significant morbidity and
mortality, as well as considerable medical resource
consumption. With the emergence of methicillinresistant S. aureus (MRSA) strains, current antibiotic
treatments are becoming ineffective in combatting S.
aureus infection. Thus, a novel therapeutic strategy is
required. Recent studies discovered that several
cytokines in the infected wound area play protective
roles against S. aureus infection. This review
summarizes recent discoveries regarding the role of
cytokines-mediated responses in host defense against S.
aureus skin infection, and discusses their implications
for future immunotherapy and vaccine development.
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Citation
Histology and Histopathology, Vol.32, nÂş8, (2017)
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