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Mechanism of experimental autoimmune neuritis in Lewis rats: the dual role of macrophages

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dc.contributor.authorShin, Taekyun
dc.contributor.authorAhn, Meejung
dc.contributor.authorMatsumoto, Yoh
dc.contributor.authorMoon, Changjong
dc.date.accessioned2018-05-15T11:28:29Z
dc.date.available2018-05-15T11:28:29Z
dc.date.issued2013
dc.description.abstractHuman peripheral demyelinating diseases, such as Guillain-Barré syndrome (GBS), are characterized by inflammation and demyelination in the peripheral nervous system. Similarities in the pathology between GBS and the animal model of experimental autoimmune neuritis (EAN) indicate that autoimmune responses are involved in both diseases. This article summarizes the general aspects of the EAN model in Lewis rats and discusses the potential role of macrophages in the progression of EAN. A better understanding of macrophages may help to design alternative therapeutic strategies for organ-specific autoimmune diseases, including GBS.es
dc.formatapplication/pdfes
dc.format.extent6es
dc.identifier.citationHistology and Histopathology, vol. 28, nº 6, (2013)
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/58401
dc.languageenges
dc.publisherF. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histologíaes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectAlternatively activated macrophageses
dc.subjectExperimental autoimmune neuritises
dc.subjectGuillain-Barré syndromees
dc.subjectPeripheral nervous system inflammationes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleMechanism of experimental autoimmune neuritis in Lewis rats: the dual role of macrophageses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.28, nº 6 (2013)