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Diagnosis of Hodgkin`s disease: an update on histopathological and immunophenotypical features

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dc.contributor.authorFraga, M.es
dc.contributor.authorForteza, J.es
dc.date.accessioned2012-05-21T12:10:35Z
dc.date.available2012-05-21T12:10:35Z
dc.date.issued2007
dc.description.abstractThe Hodgkin lymphoma (HL) is a B-cell lymphoma, as was proved by molecular studies with single-cell PCR. Histologically, it is characterized by a minority of neoplastic cells, Reed-Sternberg cells and its variants, related to a variable non-neoplastic inflammatory background. Nowadays, (WHO classification) the following types of HL are recognized: Nodular Paragranuloma and the Classical Hodgkin Lymphoma, the latter including Nodular Sclerosis, Mixed Cellularity, Lymphocyte-rich Classical Hodgkin Lymphoma and Lymphocyte Depletion. Morphology together with immunohistochemical studies allows to classify the different forms of Hodgkin lymphoma and to make a differential diagnosis with non-Hodgkin lymphomas. All classical Hodgkin lymphomas are treated similarly, and chances for remission and survival are currently good. Molecular parameters should be added to the current classification and patients could benefit from new therapeutic targets.es
dc.formatapplication/pdfes
dc.format.extent13es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/27620
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectHodgkin lymphomaes
dc.subjectImmunophenotypees
dc.subject.other616 - Patología. Medicina clínica. Oncologíaes
dc.titleDiagnosis of Hodgkin`s disease: an update on histopathological and immunophenotypical featureses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.22, nº 8 (2007)