Publication:
Morphological changes induced by colchicine in the chick optic cup in early stages of development. A stereological study

Simple item page
dc.contributor.authorAbadía Molina, F.es
dc.contributor.authorCalvente, R.es
dc.contributor.authorCarmona Martos, R.
dc.contributor.authorLuján, R.
dc.contributor.authorAbadía Fenoll, F.
dc.date.accessioned2011-02-01T09:16:20Z
dc.date.available2011-02-01T09:16:20Z
dc.date.issued1999
dc.description.abstractIn this study chick embryo optic cups at HH stage 13 of development were analyzed under normal conditions and after inoculation with colchicine for 1, 2, 4, and 8 h. Several changes were seen after these periods of treatment: 1) modifications of the structure, with thicker regions in the cup and a general decrease in the total volume according to the duration of exposure to the drug (about 4 times less than normal, 5,035 x lo3 ym3 vs 1,334 x lo3 ym3 after 8 h of treatrnent); 2) enlargement of the ventricular cavity and its closure, due to failure of approximation of retina1 and pigmentary layers; 3) failure of lens development, with delay and impairment of pit formation and deformation of al1 structures; lens volume was less than normal (about 4 times less, 2,148 x 103 pm3 vs 658 x lo3 pm3. after 8 h of treatment); 4) a general segregation of the cells making up the structure, principally in the more active proliferating zones. The local alterations found are describedes
dc.formatapplication/pdfes
dc.format.extent8es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18391
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectStereologyes
dc.subjectColchicinees
dc.subject.otherCDU::5 - Ciencias puras y naturales::57 - Biología::576 - Biología celular y subcelular. Citologíaes
dc.titleMorphological changes induced by colchicine in the chick optic cup in early stages of development. A stereological studyes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Morphological changes induced by colchicine in the chick optic cup in early stages of development. A stereological study.pdf
Size:
3.74 MB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Histology and histopathology Vol. 8, nº 2 (1993)