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Ultrastructural study of neuromuscular junction in rectus femoris muscle of streptozotocin-diabetic rats

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dc.contributor.authorMedina sánchez, M.es
dc.contributor.authorRodríguez Sáchez, C.es
dc.contributor.authorVega Alvarez, J.A.
dc.contributor.authorMenéndez Peláez, A.
dc.date.accessioned2011-02-01T08:47:57Z
dc.date.available2011-02-01T08:47:57Z
dc.date.issued1992
dc.description.abstractThe neuromuscular junctions (NMJ) from rectus femoris muscle in streptozotocin (STZ) -induced diabetic rats were examined by electron microscopy eight weeks after the STZ injection. When compared to controls and vehicle-injected groups, both the axon terminal and the junctional sarcoplasm showed serious alterations including mitochondrial degeneration, presence of myeloid bodies, breakdown of presynaptic membrane and changes in the form of the synaptic vesicles. The results suggest that NMJ can contribute to the pathogenesis of diabetic proximal myopathy.es
dc.formatapplication/pdfes
dc.format.extent4es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18360
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectQuadriceps musclees
dc.subjectNeuromuscular junctiones
dc.subject.otherCDU::5 - Ciencias puras y naturales::57 - Biología::576 - Biología celular y subcelular. Citologíaes
dc.titleUltrastructural study of neuromuscular junction in rectus femoris muscle of streptozotocin-diabetic ratses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol. 7, nº 4 (1992)