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The role of RhoC in malignant tumor invasion, metastasis and targeted therapy

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dc.contributor.authorGuan, Xue
dc.contributor.authorChen, Shuo
dc.contributor.authorZhao, Yang
dc.date.accessioned2022-04-05T07:44:36Z
dc.date.available2022-04-05T07:44:36Z
dc.date.issued2018
dc.description.abstractAs an important member of the RhoGTPase family, RhoC has various biological functions, such as regulating cytoskeleton reorganization, influencing cell adhesion, and migration. During recent decades, RhoC has been proven to be involved in the invasion and metastasis of malignant tumor and is thus a promising target of tumor therapy. This review focuses on the molecular mechanism of RhoC in invasion and metastasis of malignant tumors, as well as its research prospects as a potential target for tumor therapy.es
dc.formatapplication/pdfes
dc.format.extent6es
dc.identifier.citationHistology and Histopathology, Vol.33, nÂş3, (2018)
dc.identifier.doiDOI: 10.14670/HH-11-915
dc.identifier.issn1699-5848
dc.identifier.issn0213-3911
dc.identifier.urihttp://hdl.handle.net/10201/118705
dc.languageenges
dc.publisherUniversidad de Murcia. Departamento de BiologĂ­a Celular e HistologĂ­aes
dc.relationSin financiaciĂłn externa a la Universidades
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectRhoCes
dc.subjectMalignant tumores
dc.subjectInvasiones
dc.subjectMetastasises
dc.subjectTargeted therapyes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - PatologĂ­a. Medicina clĂ­nica. OncologĂ­aes
dc.titleThe role of RhoC in malignant tumor invasion, metastasis and targeted therapyes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.33, nÂş3 (2018)