Publication:
The role of RhoC in malignant tumor invasion, metastasis and targeted therapy

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Guan-33-255-260-2018.pdf(115.25 KB)
Date
2018
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Authors
Guan, Xue ; Chen, Shuo ; Zhao, Yang
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Publisher
Universidad de Murcia. Departamento de BiologĂ­a Celular e HistologĂ­a
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DOI
DOI: 10.14670/HH-11-915
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info:eu-repo/semantics/article
Description
Abstract
As an important member of the RhoGTPase family, RhoC has various biological functions, such as regulating cytoskeleton reorganization, influencing cell adhesion, and migration. During recent decades, RhoC has been proven to be involved in the invasion and metastasis of malignant tumor and is thus a promising target of tumor therapy. This review focuses on the molecular mechanism of RhoC in invasion and metastasis of malignant tumors, as well as its research prospects as a potential target for tumor therapy.
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RhoC , Malignant tumor , Invasion , Metastasis , Targeted therapy
Citation
Histology and Histopathology, Vol.33, nÂş3, (2018)
URI
http://hdl.handle.net/10201/118705
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Collections
Histology and histopathology Vol.33, nÂş3 (2018)
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