Publication:
Monoclonal antibody against histiocytosis X cells

dc.contributor.authorIshikawa, Makotoes
dc.contributor.authorMatsuda, Mikioes
dc.contributor.authorlmai, Yutaka
dc.date.accessioned2011-02-01T08:47:17Z
dc.date.available2011-02-01T08:47:17Z
dc.date.issued1992
dc.description.abstractMonoclonal antibody against histiocytosis X cells (HXCs) was established. The antigen was the cell membrane of HXCs from the submandibular lesion of a 63-year-old man who had been dignosed as an adult type of histiocytosis X (HX) and whose HXCs had numerous Birbeck granules (BGs). The obtained monoclonal antibody, named MI1, reacted with the antigenic cell membrane of HXC. Immunoblotting showed that MI1 bound to the cell membrane of 28500 mw. MI1 also reacted with interdigitating reticulum cells (IDCs) in the tonsil and Langerhans cells (LCs) in the epidermis. MI1 reacted with the BGs which connected to the cell membrane, but not with those located near the nucleus.es
dc.formatapplication/pdfes
dc.format.extent9es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18322
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectHistiocytosis Xes
dc.subjectBirbeck granulees
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleMonoclonal antibody against histiocytosis X cellses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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