Publication:
lmmunohistochemical study of intracranial cysts

Simple item page
dc.contributor.authorCoca, S.es
dc.contributor.authorMartínez, A.es
dc.contributor.authorVaquero, J.
dc.contributor.authorMoreno M.
dc.contributor.authorMartos, J.A.
dc.contributor.authorRodríguez, J.
dc.contributor.authorMata, P.
dc.date.accessioned2011-02-01T09:17:11Z
dc.date.available2011-02-01T09:17:11Z
dc.date.issued1993
dc.description.abstractWe present the irnmunohistochernical study of 11 cases of intracranial cysts: two extraventricular ependymal cysts, three colloid cysts of the third ventricle, four extraventricular choroidal cysts and two Rathke's cleft cysts. Antibodies against glial fibrillary acidic protein (GFAP), cytokeratins (AE1, CKSD, AE3), S-100 protein, epithelial membrane antigen (EMA), vimentin, neuron specific enolase (NSE), neurofilaments protein (NF) and prealbumin, were used. The epithelium of choroidal cysts, showed strong immunoreactivity for Prealbumin and cytokeratins, similar to the normal choroid plexus epithelium. The ependymal cysts showed epithelial immunoreactivity for GFAP and S-100, both glial markers expressed by the normal ependymal epithelium. On the contrary, the epithelial wall of colloid cysts and Rathke's cleft cyst, expressed epithelial markers (cytokeratins and EMA) but no neuroepithelial markers, with a immuno-phenotype similar to that of other cysts of endodermal nature. This finding supports the neuroepithelial origin for choroid and ependymal cysts, and an endodermal nature for colloid and Rathke's cleft cysts. We conclude that these immunohistochernical markers are useful in the differential diagnosis of intracranial cystses
dc.formatapplication/pdfes
dc.format.extent4es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/18441
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectIntracranial cystses
dc.subjectImmunohistochemical studyes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncologíaes
dc.titlelmmunohistochemical study of intracranial cystses
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
lmmunohistochemical study of intracranial cysts.pdf
Size:
684.92 KB
Format:
Adobe Portable Document Format
Description:
Download
Collections
Histology and histopathology Vol. 8, nº 4 (1993)