Publication: Human postmenopausal ovary - hormonally inactive fibrous connective tissue or more
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Date
2008
Authors
Laszczynska, M. ; Brodowska, A. ; Starczewski, A. ; Masiuk, M. ; Brodowski, J.
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
The ovary undergoes several changes after
the menopause. In this period, the main structural
changes in both the cortex and medulla were observed.
In the cortex, they included: 1) reduction of its thickness;
2) epithelial inclusions forming cysts; 3) blurring the line
between medulla and cortex; 4) reduction of follicles
number; 5) tendency to fragmentation of corpora
albicantia; 6) surface epithelium invaginations. Whereas
the changes in the medulla included: 1) fibrosis and
scars in stroma; 2) architectonical changes in blood
vessels with hyalinization of walls and constriction of
lumen. The loss of follicles and several changes in the
ovary are due to apoptotic processes. Despite age related
atrophic changes, the postmenopausal ovary is not
devoid of hormonal activity. Our results are coherent
with the reports of other researchers, and reveal that
postmenopausal ovary produces trace quantities of
steroid hormones, mainly androgens, and confirm the
presence of steroid receptors and activity of main
enzymes involved in steroidogenesis process.
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Citation
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