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Role of Müller glia in neuroprotection and regeneration in the retina

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dc.contributor.authorGarcía, M.es
dc.contributor.authorVecino, E.es
dc.date.accessioned2011-06-08T09:04:09Z
dc.date.available2011-06-08T09:04:09Z
dc.date.issued2003
dc.description.abstractGlial cells are thought to protect neurons from various neurological insults. When there is injury to retina, Müller cells, which are the predominant glial element in the retina, undergo significant morphological, cellular and molecular changes. Some of these changes reflect Müller cell involvement in protecting the retina from further damage. Müller cells express growth factors, neurotransmitter transporters and antioxidant agents that could have an important role in preventing excitotoxic damage to retinal neurons. Moreover, Müller cells contact to endothelial cells to facilitate the neovascularization process during hypoxic conditions. Finally, recent studies have pointed to a role of Müller cells in retina regeneration after damage, dedifferentiating to progenitor cells and then giving rise to different neuronal cell types. In this article we will review the role of Müller glia in neuroprotection and regeneration after damage in the retina.es
dc.formatapplication/pdfes
dc.format.extent14es
dc.identifier.issn0213-3911es
dc.identifier.urihttp://hdl.handle.net/10201/21497
dc.languageenges
dc.publisherMurcia : F. Hernándezes
dc.relation.ispartofHistology and histopathologyes
dc.rightsinfo:eu-repo/semantics/openAccesses
dc.subjectNeuroprotectiones
dc.subjectRetinaes
dc.subject.otherCDU::6 - Ciencias aplicadas::61 - Medicinaes
dc.titleRole of Müller glia in neuroprotection and regeneration in the retinaes
dc.typeinfo:eu-repo/semantics/articlees
dspace.entity.typePublicationes
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Histology and histopathology Vol.18, nº 4 (2003)