Publication: Particular functions of estrogen and progesterone in establishment of uterine receptivity and embryo implantation
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Date
2010
Authors
Ozturk, Saffet ; Demir, Ramazan
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Publisher
Murcia : F. Hernández
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DOI
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info:eu-repo/semantics/article
Description
Abstract
The process of embryo implantation requires
synchronized development of blastocyst and timely
establishment of uterine receptivity. Establishment of
uterine receptivity, preimplantation embryo development
and embryo implantation events are mainly regulated by
certain factors, including cytokines, chemokines, growth
factors and steroid hormones. Recent studies suggest that
steroid hormones, especially estrogen and progesterone,
play important roles in supporting endometrial
preparations to establish endometrial receptivity. Timely
establishment of endometrial receptivity is a crucial
process for providing successful embryo implantation.
Although many investigations until now have been
performed to precisely understand the effects of estrogen
and progesterone on acquiring uterine receptivity and
embryo implantation in humans and rodents, there are
limited numbers of studies that largely focus on this
subject. Therefore, in this article we discuss the studies
associated with significant functions of estrogen and
progesterone in establishing receptive endometrium and
the process of embryo implantation in humans and
rodents.
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