Patient iPSC-derived retinal organoids: Observable retinal diseases in-a-dish

Zhang, Xiao-Hui; Jin, Zi-Bing

Publication:
Patient iPSC-derived retinal organoids: Observable retinal diseases in-a-dish

dc.contributor.author	Zhang, Xiao-Hui
dc.contributor.author	Jin, Zi-Bing
dc.date.accessioned	2023-01-19T09:13:15Z
dc.date.available	2023-01-19T09:13:15Z
dc.date.issued	2021
dc.description.abstract	Induced pluripotent stem cells (iPSCs), reprogrammed from human somatic cells, hold the capacity to differentiate into most human body cells. iPSCs can be differentiated into retinal organoids, a three-dimensional structured retina containing various retinal cells. Patient-specific retinal organoids provide a powerful disease model to recapitulate the disease to study the pathogenesis of inherited retinal dystrophies, to screen or discover new drugs, and most importantly to supply an unlimited cell source for retinal regeneration	es
dc.format	application/pdf	es
dc.format.extent	6	es
dc.identifier.citation	Histology and Histopathology Vol. 36, nº7 (2021)
dc.identifier.doi	https://doi.org/10.14670/HH-18-307
dc.identifier.issn	0213-3911
dc.identifier.issn	1699-5848
dc.identifier.uri	http://hdl.handle.net/10201/127527
dc.language	eng	es
dc.publisher	Universidad de Murcia, Departamento de Biologia Celular e Histiologia	es
dc.relation	Sin financiación externa a la Universidad	es
dc.rights	info:eu-repo/semantics/openAccess	es
dc.rights	Attribution-NonCommercial-NoDerivatives 4.0 Internacional	*
dc.rights.uri	http://creativecommons.org/licenses/by-nc-nd/4.0/	*
dc.subject	Induced pluripotent stem cells	es
dc.subject	Retinal organoids	es
dc.subject	Inherited retinal dystrophy	es
dc.subject	Gene editing	es
dc.subject	Disease modeling	es
dc.subject.other	CDU::6 - Ciencias aplicadas::61 - Medicina::616 - Patología. Medicina clínica. Oncología	es
dc.title	Patient iPSC-derived retinal organoids: Observable retinal diseases in-a-dish	es
dc.type	info:eu-repo/semantics/article	es
dspace.entity.type	Publication	es